Nature of intestinal microflora disorders in cardiovascular diseases

The article reviews the literature on relationship between intestinal microflora and cardiometabolic disorders. pathophysiological significance of disturbance in development pathology has long been known proven. However, scientific research recent decades convincingly proven that positive role microbiota is not limited only to intestines. Disturbances can affect other organs systems, particular, processes. mechanism dysbiotic disorders cardiovascular system occur due deterioration barrier function through influence various metabolites When deteriorates, pro-inflammatory harmful components such as lipopolysaccharides have a negative effect system. Short-chain fatty acids, bile trimethylamine N-oxide are greatest importance among microflora, which diverse Accumulated data indicate possible impact disturbances atherosclerosis, hypertension, chronic heart failure. search for methods correcting flora underway, would allow eliminate specified impact.